ONE MERCK FOR MALARIA PROGRAM: AN INTEGRATED R&D APPROACH TO FIGHT AGAINST MALARIA

Metabolomics in the fight against malaria

Metabolomics uses high-resolution mass spectrometry to provide a chemical fingerprint of thousands of metabolites present in cells, tissues or body fluids. Such metabolic phenotyping has been successfully used to study various biologic processes and disease states. High-resolution metabolomics can shed new light on the intricacies of host-parasite interactions in each stage of the Plasmodium li...

[Progress in the fight against malaria].

• In 2007, the U.S. provided $257 million in funding for bilateral programs to fight malaria. Twenty‐five million people, most of these children, in 15 countries have been reached through these investments. • The U.S. has disbursed more than $2.5 billion to the Global Fund to Fight AIDS, Tuberculosis, and Malaria, a key partner in the fight against malaria, since its inception. The Global Fund ...

A Dam Problem : TVA ' s Fight Against Malaria 1926

The TVA has long been held in high esteem for its programs designed to reduce malaria mortality and morbidity rates in the Southeast following its establishment in 1933. One reason why the TVA developed the anti-malaria programs was that they created large bodies of standing water by damming up the Tennessee River and its tributaries. Given the recent increase in river system management project...

[Crowdsourcing as a methodology in the fight against malaria].

Antimalarials and the fight against malaria in Brazil

Malaria, known as the "fevers," has been treated for over three thousand years in China with extracts of plants of the genus Artemisia (including Artemisia annua, A. opiacea, and A. lancea) from which the active compound is artemisin, a sesquiterpene that is highly effective in the treatment of the disease, especially against young forms of the parasite. South American Indians in the seventeent...